I-CBDA, i-cannabidiolic acid, iyinhlanganisela eyenzeka ngokwemvelo etholakala esitshalweni se-cannabis. Kuyisandulela se-CBD, okusho ukuthi lapho isitshalo sensangu sicutshungulwa i-CBD iguqulwa ibe yi-CBD.
I-CBDA kucatshangwa ukuthi isebenzisana nohlelo lwe-endocannabinoid, olulawula ama-receptors e-CB1 kanye ne-CB2.
Ama-receptors e-CB1 angalawula:
- Brain
- Amangqamuzana Amafutha
- Umgogodla
- Izinso
- I-Adrenal Gland
- Amapulazi
Yize ucwaningo olwengeziwe ludingeka ukuze kuqondwe imithelela yalo emzimbeni, olunye ucwaningo lukhombisa ukwethembisa nge-CBDA ngokungezwani nokungakhululeki.
Ngokungafani ne-CBD, uwoyela we-CBDa awakakhishwa i-decarboxylated, okusho ukuthi awakashiswa ukuze kusebenze inhlanganisela. Lokhu kusho ukuthi uwoyela we-CBDa ungaba nemiphumela ehluke kancane kunezinye izinhlobo zikawoyela we-CBD.
E-United States, i-CBDa yagunyazwa ngokusemthethweni uMthethosivivinywa wePulazi ka-2018. Umthethosivivinywa Wepulazi ugunyaze ukukhiqizwa nokudayiswa kwe-CBD etholakala ku-hemp, inqobo nje uma iqukethe ngaphansi kuka-0.3% we-THC.
Ama-receptors e-CB2 angalawula:
- bone
- Brain
- Isistimu Yenhliziyo
- Umgudu Wokugaya ukudla
- izivikeli mzimba
- I-Pancreas
I-CBDA iyinhlanganisela eyenzeka ngokwemvelo etholakala esitshalweni sensangu, ngakho-ke itholakala ezinhlobonhlobo zezinhlobo zensangu.
Ngenkathi i-CBD ithole ukuthandwa eminyakeni yamuva nje ngezinzuzo zayo ezingaba khona, i-CBDA ayaziwa kangako. Uma ucabanga ukusebenzisa CBDA njengengxenye yakho Wellness isimiso, ungase ube nemibuzo mayelana nendlela esebenza ngayo, izinzuzo zayo ezingaba khona, kanye nendlela yokuyisebenzisa ngokuphepha. Kulokhu okuthunyelwe kwebhulogi, sizophendula eminye yemibuzo evame kakhulu mayelana ne-CBDA ukukusiza wenze isinqumo esinolwazi mayelana nokuthi ikulungele yini.
CBDa vs CBD | Zihluke kanjani?
CBDA, noma i-cannabidiolic acid, iyinhlanganisela eyenzeka ngokwemvelo etholakala esitshalweni se-cannabis. Iyisandulela se-CBD, okusho ukuthi lapho isitshalo sensangu sicutshungulwa, i-CBDA iguqulwa ibe yi-CBD. Umehluko omkhulu phakathi kwe-CBDA nezinye izinhlobo zikawoyela we-CBD ukuthi i-CBDA ayikakhishwa i-decarboxylated, okusho ukuthi ayikashiswa ukuze kusebenze inhlanganisela. Lokhu kusho ukuthi uwoyela we-CBDa ungaba nemiphumela ehluke kancane kunezinye izinhlobo zikawoyela we-CBD. Abanye abantu bangakhetha uwoyela we-CBD ngezinzuzo zawo zempilo ezingaba khona, kanti abanye bangakhetha ezinye izinhlobo ze-CBD.
Iyini i-CBDA futhi iyini imiphumela yayo emzimbeni womuntu?
Umzimba womuntu unohlelo lwe-endocannabinoid (ECS) olubamba iqhaza ekulawuleni imisebenzi eyahlukene, okuhlanganisa ubuthongo, isifiso sokudla, ubuhlungu, Futhi isimo sengqondo. Njengamanye ama-cannabinoids, i-CBDA kucatshangwa ukuthi isebenzisana ne-ECS, engase isize ukulawula le misebenzi emzimbeni.
Ingabe i-CBDA ingasetshenziswa ukwelapha izimo zezokwelapha?
I-CBDA, njengamanye ama-cannabinoids, kucatshangwa ukuthi inezinzuzo ezingaba khona zezempilo, kodwa ucwaningo olwengeziwe luyadingeka ukuze kuqondwe imiphumela yayo emzimbeni womuntu.
Ucwaningo olwenziwa ngo-2013 lwahlola amagundane kanye nemiphumela ye-CBDA ku-nausea nokuhlanza (Bolognin et al.).
Olunye ucwaningo olwenziwa ngo-2021 lwahlola amagundane kanye nemiphumela ye-CBDA ekuzweleni kobuhlungu kumagundane ohlobo lwasendle (Vigli et al.).
Ingabe i-CBDA isemthethweni e-United States?
Isimo esisemthethweni samafutha e-CBDA, kanye nezinye izinhlobo ze-CBD, ziyahlukahluka kuye ngokuthi uhlala kuphi. E-United States, uMthethosivivinywa Wepulazi ka-2018 ugunyaze ukukhiqizwa nokudayiswa kwe-CBD etholakala ku-hemp, inqobo nje uma iqukethe ngaphansi kuka-0.3% we-THC. Lokhu kusho ukuthi ezifundazweni eziningi, kusemthethweni ukuthenga nokusebenzisa uwoyela we-CBDa inqobo nje uma enziwe nge-hemp futhi iqukethe amazinga aphansi e-THC. Kodwa-ke, kuhlale kuwumqondo omuhle ukuhlola imithetho yendawo yangakini ukuze wenze isiqiniseko sokuthi uyayithobela yini imithethonqubo efanele.
I-CBDA ikhishwa kanjani esitshalweni se-cannabis?
I-CBDA ikhona ngokwemvelo esitshalweni se-cannabis, ngakho-ke kufanele ikhishwe ukuze kukhiqizwe uwoyela we-CBDA. Kunezindlela eziningana ezingasetshenziswa ukukhipha i-CBDA esitshalweni, kodwa indlela evamile kakhulu ihilela ukusebenzisa i-solvent, njenge-CO2 noma i-ethanol, ukuhlukanisa i-CBDa kusuka ezintweni zezitshalo. I-solvent bese iyahwamuka, ishiye ngemuva i-CBDa ekhishiwe egxilile. Lokhu kukhishwa kungaphinde kucutshungulwe ukuze kukhiqizwe uwoyela we-CBDA, ongasetshenziswa emikhiqizweni eyahlukene, okuhlanganisa ama-tinctures, okudliwayo, kanye nezihloko.
Yimiphi imiphumela emibi engaba khona kawoyela we-CBDA neminye imikhiqizo?
Njenganoma yisiphi isengezo noma umuthi, akhona amathuba okuba nemiphumela engemihle uma usebenzisa uwoyela we-CBDA. Umphumela ovame kakhulu we-CBD ukozela, ngakho-ke kubalulekile ukuqaphela uma usebenzisa imishini esindayo noma ushayela ngemuva kokuthatha uwoyela we-CBDa. Abanye abantu bangase futhi babe nomlomo owomile, isifo sohudo, noma izinguquko esifiso sokudla lapho usebenzisa uwoyela we-CBDa. Uma uhlangabezana nanoma yimiphi imiphumela emibi kakhulu noma ephathelene nemiphumela engemihle, kubalulekile ukuyeka ukusebenzisa umkhiqizo bese ubonana nomhlinzeki wezempilo. Kuhlale kuwumqondo omuhle ukukhuluma nomhlinzeki wakho wezempilo ngaphambi kokusebenzisa uwoyela we-CBDa, ikakhulukazi uma ukhulelwe, uncelisa, noma uthatha noma yimiphi imithi.
Ifomula efakiwe
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Ngabe uwoyela we-CBDA uqhathaniswa kanjani nezinye izinhlobo ze-CBD, njenge-CBD ihlukanisa noma uwoyela we-CBD ogcwele spectrum?
Uwoyela we-CBDA uhlukile kwezinye izinhlobo ze-CBD, njenge-CBD ihlukanisa namafutha e-CBD agcwele, ngezindlela ezimbalwa ezibalulekile. Ukuhlukaniswa kwe-CBD kuwuhlobo lwe-CBD olucutshunguliwe ukuze lususe zonke ezinye izinhlanganisela esitshalweni sensangu, okuhlanganisa i-THC namanye ama-cannabinoids. Lokhu kusho ukuthi ukuhlukaniswa kwe-CBD kuyindlela emsulwa ye-CBD, azikho ezinye izinhlanganisela ezikhona. Ngakolunye uhlangothi, uwoyela we-CBD ogcwele i-spectrum, uqukethe uchungechunge lwezinye izinhlanganisela ezivela esitshalweni sensangu, okuhlanganisa i-THC namanye ama-cannabinoids. Lokhu kusho ukuthi uwoyela we-CBD ogcwele i-spectrum ungaba nohlu olubanzi lwemiphumela, kodwa futhi kusho ukuthi angaba namanani omkhondo we-THC.
Ingabe uwoyela we-CBDA utholakala ezinhlobonhlobo zezinhlobo ze-cannabis, noma utholakala kuphela ezinhlotsheni ezithile zezitshalo ze-cannabis?
I-CBDA iyinhlanganisela eyenzeka ngokwemvelo etholakala esitshalweni sensangu, ngakho-ke itholakala ezinhlobonhlobo zezinhlobo zensangu. Ikhona kuzo zombili izitshalo ze-hemp nensangu, nakuba inani le-CBDA kunoma yiluphi uhlobo lohlobo oluthile lingahluka ngokuya ngezinto ezimbalwa, okuhlanganisa ufuzo lwesitshalo kanye nezimo ezikhulayo. Ezinye izinhlobo zensangu zingase zibe namazinga aphezulu e-CBDA kunezinye, ngakho-ke uma ufuna uhlobo oluthile oluphezulu e-CBDA, kuwumqondo omuhle ukubuza indawo yangakini noma uhlole ukulebula komkhiqizo ukuze ubone ukuthi ingakanani i-CBDA ekhona. emkhiqizweni.
Ingabe i-CBDA ingasetshenziswa ngokuhlanganiswa namanye ama-cannabinoids ukuthuthukisa imiphumela yawo noma ukunikeza umuzwa olinganiselayo, ogcwele kahle?
Imikhiqizo ye-CBDA ingasetshenziswa ngokuhlangana namanye ama-cannabinoids ukuthuthukisa imiphumela yawo noma ukunikeza umuzwa olinganiselayo, ogcwele kahle. Lokhu kungenxa yokuthi i-CBDA, njengamanye ama-cannabinoids, kucatshangwa ukuthi isebenzisana nohlelo lomzimba lwe-endocannabinoid (ECS), olubamba iqhaza ekulawuleni imisebenzi eyahlukene, okuhlanganisa ukulala, isifiso sokudla, izinhlungu, nomoya. Ngokuhlanganisa i-CBDa namanye ama-cannabinoids, njenge-CBD noma i-THC, kungenzeka udale umkhiqizo onohlu olubanzi lwezinzuzo ezingaba khona. Kodwa-ke, ucwaningo olwengeziwe luyadingeka ukuze kuqondwe imiphumela ethile yokuhlanganisa ama-cannabinoids ahlukahlukene. Kuhlale kubalulekile ukubonisana nomhlinzeki wezempilo ngaphambi kokusebenzisa noma yiluphi uhlobo lwesithasiselo noma okunye ukwelashwa, okuhlanganisa uwoyela we-CBDa.
Sengiphetha, i-CBDA iyinhlanganisela eyenzeka ngokwemvelo etholakala esitshalweni se-cannabis okucatshangwa ukuthi inezinzuzo ezingaba khona. Yize ucwaningo olwengeziwe ludingeka ukuze uqonde ngokugcwele imiphumela ye-CBDA emzimbeni womuntu, kucatshangwa ukuthi isebenzisana nohlelo lwe-endocannabinoid ngendlela engasiza ukulawula imisebenzi eyahlukene emzimbeni. Uma ucabanga ukusebenzisa i-CBDA njengengxenye yendlela yakho yokuphila kahle, kubalulekile ukukhuluma nomhlinzeki wezempilo ukuze uqinisekise ukuthi kuphephile kuwe futhi uqonde umthamo nokuphatha okufanele. Ngokulandela imihlahlandlela efanele nokusebenzisa imikhiqizo yekhwalithi ephezulu, i-CBDA ingaba yindlela engokwemvelo nesebenzayo yokusekela impilo yakho yonke kanye nempilo yakho.
Imihlahlandlela eminingi ye-CBD | Ukukukhethela Imikhiqizo Elungile ye-CBD
